Kratom and 7-OH: What You Should Know

Kratom and products containing 7-hydroxymitragynine (7-OH) are becoming more common in everyday retail spaces and are often marketed as “natural” or wellness products. Their availability can make them seem safe. However, there are real risks to be aware of.

What is Kratom?

large green leaves of the Mitragyna speciosa tree — Leaves of *Mitragyna speciosa*

Kratom comes from the leaves of a tropical tree called Mitragyna speciosa. One of its strongest compounds, 7-OH, acts on opioid receptors in the brain and can produce opioid-like effects. Depending on the dose, kratom may act as a stimulant or a sedative. In the plant, 7-OH is a minor component.

But in U.S. products, some manufacturers boost it, sometimes even adding semi-synthetic versions, to intensify the effects. This is a major reason we’re seeing more concerning outcomes here than would be expected from traditional use.

Health Risks

Kratom and 7-OH may lead to addiction, overdose, and in some cases, death, especially when combined with other substances. Side effects may include dependence and withdrawal, anxiety, insomnia, seizures, nausea, and dangerous slowing of breathing. Despite marketing claims, there is no reliable evidence that kratom or 7-OH safely treats pain, anxiety, or opioid withdrawal.

Kratom products do not have consistent dosing, and there is no universally established safe dosage. As such, there is no guidance on what amount of kratom is “a little” or “a lot.” Consuming a kratom product has real risks and dangers when the exact measurements of the substance are unknown.

What to Watch For

There are currently no specific local policies in Marin County that ban kratom. However, kratom and 7-OH are not approved by the U.S. Food and Drug Administration (FDA) as a food, drug, or dietary supplement. Thus, the California Department of Public Health (CDPH) uses these standards to point out that any substance not approved by the FDA is not legal to manufacture or sell for consumption.

Additionally, California Health & Safety Code 110555 states that “any food is adulterated if it is, bears, or contains any food additive that is unsafe within the meaning of Section 110445.” According to the CDPH, kratom and 7-OH are unsafe, and so foods containing them are considered to be adulterated.

kratom powder, which is a warm, sage green color, is sold to look like a health product — Kratom powder

Even so, these products are found in stores, and even more easily online, and are often designed to look like candy, beverages, or health supplements. Products are sold in forms such as gummies, “health shots,” powders, capsules, or tablets. Always read labels carefully and be cautious of products that make unverified health claims.

Community voices play an important role in shaping local policy. County ordinances can be created or updated when community members speak up about emerging public health concerns. Staying informed and engaged helps ensure that policies reflect the needs and safety of our community. To report the illegal sale of 7-OH, individuals can call Public Health Environmental Health at 415-473-6907.

Naloxone can reverse overdoses involving opioids, including those related to 7-OH. Carrying naloxone and knowing how to use it can save a life. Free naloxone is available throughout Marin County!